The village is home to a majority of Dhillon Jatt Sikhs. this village in the district of Tarn-Taran, located in the north-west of Punjab. D) Phylogenetic tree of cellobiohydrolases gene family OG_03_0001111.Kairon, is a small historical Indian village of the historical places like ਗੁਰੁਦੁਆਰਾ ਝਾੜ ਸਾਹਿਬ ( ਪਾਤਸ਼ਾਹੀ ਪੰਜਵੀ ਧੰਨ ਸ਼੍ਰੀ ਗੁਰੂ ਅਰਜਨ ਦੇਵ ਜੀ) Gurudwara Jhar Sahib. There are a total of 23 sequences with this label, from 10 different species. C) The proportion of sequences in the cellobiohydrolases Gene Family: OG_03_0001111. The bars and the dots indicate the average and minimum/maximum values of the RNA-seq experiments in the sample. The different samples are represented on the x-axis, while the gene expression values in the form of Transcripts Per Million (TPM) are indicated on the y-axis. Only part of the expression profile containing the discussed sample is shown. B) Average expression profile of cluster 21 for Cci. Colored shapes indicate which genes contain Pfam domains and orthogroups in common. For brevity, novel genes (hypothetical proteins) are not shown in the network.

Nodes represent genes, while co-expressed genes are connected by edges. A) Coexpression network of genes identified as enriched for GO:0030245 (GO term for Cellulose Catabolic Process). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)Ĭluster analysis involved in cellulose catabolic process in Coprinopsis cinerea.

For brevity, only the discussed genes are shown, and the nodes are arranged for better clarity. The function of the genes can be inferred from the legend and by clicking on the nodes. The network contains four types of genes: gliotoxin family genes (indicated in the red rectangle), genes involved in protein synthesis (blue rectangle), metabolite transporters (orange rectangle), and decorating enzymes (green rectangle). For brevity, only part of the network is shown. Nodes represent genes, while edges connect co-expressed genes. The bars and the dots indicate the average and the minimum/maximum values of the RNA-seq experiments in the sample, respectively. B) Expression profile of EAL85149, a nonribosomal peptide synthase ftmA that shows the highest connection to other backbone enzymes. The plot was generated by exporting the network file and opening the file in standalone Cytoscape. The color of the node indicates the type of backbone enzyme. For brevity, enzymes that are not co-expressed are not shown. A) Coexpression network of the backbone enzymes involved in specialized metabolism.

The tool is available at Keywords:Ĭo-expression Database Expression Fungi Gene function Metabolism.Ĭoexpression analysis of specialized metabolic hubs in Aspergillus fumigatus. We exemplify how our tool can elucidate the molecular function, biological process and cellular component of genes involved in various biological processes, by identifying a secondary metabolite pathway producing gliotoxin in Aspergillus fumigatus, the catabolic pathway of cellulose in Coprinopsis cinerea and the conserved DNA replication pathway in Fusarium graminearum and Pyricularia oryzae. To help remedy this, we gathered genomic and gene expression data of 19 most widely-researched fungi to build an online tool,, which contains tools for cross-species identification of conserved pathways, functional gene modules, and gene families. However, our lack of knowledge of gene function in fungi precludes us from tailoring them to our needs and tapping into their metabolic diversity. They also produce a vast diversity of secondary metabolites, which have antibiotic or pharmacological properties. The fungi kingdom is composed of eukaryotic heterotrophs, which are responsible for balancing the ecosystem and play a major role as decomposers.

Kairon singh